Disease caused by deficiency of Vitamin-D (Calciferol) is :

Question

Accepted Answer

Disease caused by deficiency of Vitamin-D (Calciferol) is:

Correct Answer: Option 4 - Rickets

Explanation:

1. **Why Option 4 is Correct:**
   - Rickets is a disease that primarily affects children and is caused by a deficiency of Vitamin D, calcium, or phosphate. Vitamin D is crucial for the absorption of calcium and phosphate in the body, which are essential for healthy bone formation. When there is a deficiency of Vitamin D, the bones become soft and weak, leading to skeletal deformities, such as bowed legs or thickened wrists and ankles. This condition is known as rickets. In adults, a similar condition caused by Vitamin D deficiency is called osteomalacia.

2. **Why the Other Options are Incorrect:**
   - **Option 1: Night-blindness**
     - Night-blindness is not caused by a deficiency of Vitamin D. Instead, it is caused by a deficiency of Vitamin A. Vitamin A is essential for the production of rhodopsin, a pigment in the retina that is necessary for vision in low-light conditions. A lack of Vitamin A leads to impaired vision in dim light, known as night-blindness.
   
   - **Option 2: Beri-Beri**
     - Beri-Beri is caused by a deficiency of Vitamin B1 (thiamine), not Vitamin D. Thiamine is important for energy metabolism and nerve function. A deficiency can lead to symptoms affecting the cardiovascular and nervous systems, such as weakness, pain, and heart problems.
   
   - **Option 3: Scurvy**
     - Scurvy is caused by a deficiency of Vitamin C (ascorbic acid), not Vitamin D. Vitamin C is essential for the synthesis of collagen, which is important for the health of skin, blood vessels, and connective tissues. A deficiency in Vitamin C leads to symptoms such as bleeding gums, joint pain, and anemia.

In conclusion, the correct answer is Option 4 - Rickets, as it is directly linked to a deficiency of Vitamin D, which is essential for bone health and development. The other options are associated with deficiencies of different vitamins and result in different diseases.