Which of the following is an antidepressant drug ?

Question

Accepted Answer

Option 1, Iproniazid, is the correct answer as it is an antidepressant drug. Iproniazid belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs). It was one of the first antidepressants discovered and works by inhibiting the activity of the enzyme monoamine oxidase. This inhibition leads to an increase in the levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain, which can help alleviate symptoms of depression.

Now, let's explain why the other options are incorrect:

2. Terfenadine: Terfenadine is not an antidepressant. It is an antihistamine that was used to treat allergic conditions such as hay fever and urticaria. It works by blocking histamine receptors, which helps reduce allergy symptoms. However, it is not used for treating depression.

3. Dimetapp: Dimetapp is a brand name for a combination of drugs used to relieve symptoms of cold and allergies, such as nasal congestion and cough. It typically contains an antihistamine and a decongestant. It is not an antidepressant and does not have any effect on mood disorders.

4. Cimetidine: Cimetidine is not an antidepressant. It is a medication used to treat conditions related to excess stomach acid, such as ulcers and gastroesophageal reflux disease (GERD). It works by blocking histamine receptors in the stomach, reducing acid production. It has no role in the treatment of depression.

In summary, Iproniazid is the only option among the given choices that is classified as an antidepressant drug, specifically a monoamine oxidase inhibitor, which justifies why Option 1 is the correct answer.