Which of the following is an antidepressant drug ?

Question

Accepted Answer

Option 4, Iproniazid, is the correct answer because it is an antidepressant drug. Iproniazid belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs). It was one of the first antidepressants discovered and works by inhibiting the activity of the enzyme monoamine oxidase, which breaks down neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By preventing the breakdown of these neurotransmitters, Iproniazid increases their levels and helps alleviate symptoms of depression.

Now, let's examine why the other options are incorrect:

1. **Cimetidine**: This is not an antidepressant. Cimetidine is a medication that belongs to a class of drugs known as H2 blockers. It is primarily used to treat conditions related to excess stomach acid, such as ulcers and gastroesophageal reflux disease (GERD). It works by reducing the amount of acid produced in the stomach.

2. **Dimetapp**: This is also not an antidepressant. Dimetapp is an over-the-counter medication commonly used to relieve symptoms of cold and allergies, such as nasal congestion and runny nose. It typically contains antihistamines and decongestants, which help alleviate these symptoms but have no effect on depression.

3. **Terfenadine**: This is not an antidepressant either. Terfenadine is an antihistamine that was used to treat allergic conditions such as hay fever. It works by blocking histamine receptors in the body, thereby reducing allergy symptoms. However, it does not have any antidepressant properties.

In summary, Iproniazid is the only option among the given choices that is classified as an antidepressant drug, specifically a monoamine oxidase inhibitor, which justifies why Option 4 is the correct answer.