The correct option is 2: G-6-P dehydrogenase (G6PD) deficiency is one of the world's most common enzyme disorders, and it is intrinsically associated with the selective destruction, or hemolysis, of red blood cells (RBCs). To understand why, you must recall the role of the Pentose Phosphate Pathway (PPP). G6PD is the critical, rate-limiting enzyme in this pathway, which is the sole source of the reduced coenzyme NADPH in mature RBCs.…Read More